N-{4-[(4-Chloro-1-piperidinyl)sulfonyl]phenyl}-5-nitro-2-furamide
Modify Date: 2024-01-06 18:20:29
![N-{4-[(4-Chloro-1-piperidinyl)sulfonyl]phenyl}-5-nitro-2-furamide Structure](https://www.chemsrc.com/caspic/392/1523437-16-2.png)
N-{4-[(4-Chloro-1-piperidinyl)sulfonyl]phenyl}-5-nitro-2-furamide structure
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Common Name | N-{4-[(4-Chloro-1-piperidinyl)sulfonyl]phenyl}-5-nitro-2-furamide | ||
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| CAS Number | 1523437-16-2 | Molecular Weight | 413.83 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H16ClN3O6S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of N-{4-[(4-Chloro-1-piperidinyl)sulfonyl]phenyl}-5-nitro-2-furamideML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden[1]. |
| Name | N-{4-[(4-Chloro-1-piperidinyl)sulfonyl]phenyl}-5-nitro-2-furamide |
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| Synonym | More Synonyms |
| Description | ML291 is a UPR (unfolded protein response)-inducing sulfonamidebenzamide. ML291 overwhelms the adaptive capacity of the UPR and induces apoptosis in a variety of solid cancer models. ML291 can activate the PERK/eIF2a/CHOP (apoptotic) arm of the UPR and reduce leukemic cell burden[1]. |
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| Related Catalog | |
| References |
| Density | 1.6±0.1 g/cm3 |
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| Molecular Formula | C16H16ClN3O6S |
| Molecular Weight | 413.83 |
| Exact Mass | 413.044830 |
| LogP | 2.78 |
| Index of Refraction | 1.652 |
| RIDADR | NONH for all modes of transport |
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| N-{4-[(4-Chloro-1-piperidinyl)sulfonyl]phenyl}-5-nitro-2-furamide |
| 2-Furancarboxamide, N-[4-[(4-chloro-1-piperidinyl)sulfonyl]phenyl]-5-nitro- |