TJ191

Modify Date: 2025-11-27 19:15:58

TJ191 Structure
TJ191 structure
Common Name TJ191
CAS Number 1522415-97-9 Molecular Weight 255.376
Density N/A Boiling Point N/A
Molecular Formula C13H21NO2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TJ191


TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM); selectively targets certain cancer cells without affecting the proliferation of other cancer cells or normal fibroblasts or immune cells (over 600-fold selectivity), TβRIII acts as a predictive marker for TJ191 sensitivity in malignant T-cells.

 Names

Name TJ191

 TJ191 Biological Activity

Description TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM); selectively targets certain cancer cells without affecting the proliferation of other cancer cells or normal fibroblasts or immune cells (over 600-fold selectivity), TβRIII acts as a predictive marker for TJ191 sensitivity in malignant T-cells.
References References 1. El-Gazzar A, et al. Oncotarget. 2017 Dec 15;9(5):6259-6269. View Related Products by Target Other Targets

 Chemical & Physical Properties

Molecular Formula C13H21NO2S
Molecular Weight 255.376
InChIKey HUFNXSPJUAHQHP-UHFFFAOYSA-N
SMILES CCCCCCCc1cc(C(=O)OC)c(N)s1
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