TJ191

Names

[ Name ]:
TJ191

Biological Activity

[Description]:

TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM); selectively targets certain cancer cells without affecting the proliferation of other cancer cells or normal fibroblasts or immune cells (over 600-fold selectivity), TβRIII acts as a predictive marker for TJ191 sensitivity in malignant T-cells.

[References]

References 1. El-Gazzar A, et al. Oncotarget. 2017 Dec 15;9(5):6259-6269. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₂₁NO₂S

[ Molecular Weight ]:
255.376

Related Compounds

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