1522415-97-9
1522415-97-9 structure
- Name: TJ191
- Chemical Name: TJ191
- CAS Number: 1522415-97-9
- Molecular Formula: C13H21NO2S
- Molecular Weight: 255.376
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2020-01-20 11:24:56
- Modify Date: 2024-09-28 15:45:48
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TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM); selectively targets certain cancer cells without affecting the proliferation of other cancer cells or normal fibroblasts or immune cells (over 600-fold selectivity), TβRIII acts as a predictive marker for TJ191 sensitivity in malignant T-cells.
| Name | TJ191 |
|---|
| Description | TJ191 is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells (MOLT-3 IC50=0.26 uM); selectively targets certain cancer cells without affecting the proliferation of other cancer cells or normal fibroblasts or immune cells (over 600-fold selectivity), TβRIII acts as a predictive marker for TJ191 sensitivity in malignant T-cells. |
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| References | References 1. El-Gazzar A, et al. Oncotarget. 2017 Dec 15;9(5):6259-6269. View Related Products by Target Other Targets |
| Molecular Formula | C13H21NO2S |
|---|---|
| Molecular Weight | 255.376 |