3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone

Modify Date: 2024-04-09 11:48:27

3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone Structure
3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone structure
Common Name 3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone
CAS Number 151752-07-7 Molecular Weight 302.322
Density 1.2±0.1 g/cm3 Boiling Point 532.7±50.0 °C at 760 mmHg
Molecular Formula C17H18O5 Melting Point N/A
MSDS N/A Flash Point 196.7±23.6 °C

 Use of 3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone


4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC5050 of 15 μM[1].

 Names

Name 3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone
Synonym More Synonyms

  Biological Activity

Description 4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC5050 of 15 μM[1].
Related Catalog
Target

Estrogen receptor

In Vitro 4',2-Dihydroxy-4,6-dimethoxydihydrochalcone stimulates the MCF-7 cell proliferation in a concentration dependent manner between 10 nM and 10 μM[1].
References

[1]. K Ichikawa, et al. Retrodihydrochalcones and homoisoflavones isolated from Thai medicinal plant Dracaena loureiri and their estrogen agonist activity. Planta Med. 1997 Dec;63(6):540-3.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 532.7±50.0 °C at 760 mmHg
Molecular Formula C17H18O5
Molecular Weight 302.322
Flash Point 196.7±23.6 °C
Exact Mass 302.115417
LogP 2.80
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.594

 Synonyms

1-Propanone, 3-(2-hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-
3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone
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