151752-07-7

151752-07-7 structure

Name: 3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone
Chemical Name: 3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone
CAS Number: 151752-07-7
Molecular Formula: C₁₇H₁₈O₅
Molecular Weight: 302.322
Catalog: Research Areas Endocrinology
Create Date: 2019-12-19 22:31:48
Modify Date: 2024-04-09 11:48:27
4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC5050 of 15 μM[1].

Name	3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone
Synonyms	1-Propanone, 3-(2-hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)- 3-(2-Hydroxy-4,6-dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone

Description	4',2-Dihydroxy-4,6-dimethoxydihydrochalcone, an estrogen agonist, shows binding affinity for bovine uterine estrogen receptor with an IC5050 of 15 μM[1].
Related Catalog	Signaling Pathways >> Others >> Estrogen Receptor/ERR Research Areas >> Endocrinology
Target	Estrogen receptor
In Vitro	4',2-Dihydroxy-4,6-dimethoxydihydrochalcone stimulates the MCF-7 cell proliferation in a concentration dependent manner between 10 nM and 10 μM[1].
References	[1]. K Ichikawa, et al. Retrodihydrochalcones and homoisoflavones isolated from Thai medicinal plant Dracaena loureiri and their estrogen agonist activity. Planta Med. 1997 Dec;63(6):540-3.