FL118
Modify Date: 2025-11-29 16:54:18
FL118 structure
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Common Name | FL118 | ||
|---|---|---|---|---|
| CAS Number | 151636-76-9 | Molecular Weight | 392.36200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H16N2O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FL118(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1]. |
| Name | 10,11-(methylenedioxy)-(20R)-camptothecin |
|---|---|
| Synonym | More Synonyms |
| Description | (R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity[1]. |
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| Related Catalog | |
| In Vitro | (R)-FL118 inhibits the growth of melanoma, breast, and prostate cancer cell lines, with IC50 values of 392.7, 32.53, 129.3, 138.7, and 92.51 ng/mL in B16, MCF-7, HS578T, DU145, and MPC3 cells, respectively[1]. |
| References |
| Molecular Formula | C21H16N2O6 |
|---|---|
| Molecular Weight | 392.36200 |
| Exact Mass | 392.10100 |
| PSA | 99.88000 |
| LogP | 1.80830 |
| InChIKey | RPFYDENHBPRCTN-OAQYLSRUSA-N |
| SMILES | CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc4c(cc3nc2-1)OCO4 |
| FL118 |