UCB-5307

Modify Date: 2025-08-21 20:28:48

UCB-5307 Structure
UCB-5307 structure
 Common Name UCB-5307
CAS Number 1515887-44-1 Molecular Weight 343.42
Density N/A Boiling Point N/A
Molecular Formula C22H21N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of UCB-5307


UCB-5307 is a TNF signaling inhibitor with a KD of 9 nM. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex[1].

 Names

Name UCB-5307

 UCB-5307 Biological Activity

Description UCB-5307 is a TNF signaling inhibitor with a KD of 9 nM. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex[1].
Related Catalog
References

[1]. O'Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795.

 Chemical & Physical Properties

Molecular Formula C22H21N3O
Molecular Weight 343.42
InChIKey MKABLXAUPLCAHG-UHFFFAOYSA-N
SMILES Cc1ccc(C)c(Cn2c(C(O)c3ccncc3)nc3ccccc32)c1
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Chemsrc provides UCB-5307(CAS#:1515887-44-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of UCB-5307 are included as well.>> amp version: UCB-5307

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