4'-Hydroxy-2,4-dimethoxychalcone

Modify Date: 2024-01-10 10:29:33

4'-Hydroxy-2,4-dimethoxychalcone structure	Common Name	4'-Hydroxy-2,4-dimethoxychalcone
	CAS Number	151135-64-7	Molecular Weight	284.306
	Density	1.2±0.1 g/cm3	Boiling Point	500.1±50.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₆O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	185.8±23.6 °C

Use of 4'-Hydroxy-2,4-dimethoxychalcone

4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2].

Name	(2E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one
Synonym	More Synonyms

Description	4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC50=4.2 μM) and W2 (IC50=4.8 μM)[1].
In Vivo	4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T1/2 of 1.94 hours, a Cmax of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice[1].
References	[1]. Clare E Gutteridge, et al. In vitro biotransformation, in vivo efficacy and pharmacokinetics of antimalarial chalcones. Pharmacology. 2011;87(1-2):96-104. [2]. Qing-An Zheng, et al. Flavonoids from the Resin of Dracaena cochinchinensis. Helvetica Chimica Acta, 87(5), 1167–1171.

Density	1.2±0.1 g/cm3
Boiling Point	500.1±50.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₆O₄
Molecular Weight	284.306
Flash Point	185.8±23.6 °C
Exact Mass	284.104858
LogP	3.48
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.614
Storage condition	2-8℃

2-Propen-1-one, 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)-

(2E)-3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one

(2E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one

BioBioPha
China
Product Name: 4'-Hydroxy-2,4-dimethoxychalcone
Price: ￥2900.0/5mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

DC Chemicals Limited
China
Product Name: 4'-Hydroxy-2,4-dimethoxychalcone
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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