PD 134922

Modify Date: 2024-03-26 16:14:03

PD 134922 Structure
PD 134922 structure
Common Name PD 134922
CAS Number 150351-30-7 Molecular Weight 719.97500
Density 1.19g/cm3 Boiling Point N/A
Molecular Formula C37H61N5O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PD 134922


PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease[1].

 Names

Name (2S,4S,5S)-N-butyl-6-cyclohexyl-4-hydroxy-5-[[(2S)-2-[[(2S)-2-(morpholin-4-ylsulfonylamino)-3-phenylpropanoyl]amino]pent-4-enoyl]amino]-2-propan-2-ylhexanamide

 PD 134922 Biological Activity

Description PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease[1].
Related Catalog
Target

IC50: 15 nM (HIV-1 protease)[1]

References

[1]. Humblet CC, et al. Characterization of two structurally novel HIV-1 protease inhibitors identified by rational selection. Antiviral Res. 1993 May;21(1):73-84.  

 Chemical & Physical Properties

Density 1.19g/cm3
Molecular Formula C37H61N5O7S
Molecular Weight 719.97500
Exact Mass 719.42900
PSA 185.02000
LogP 7.15040
Index of Refraction 1.565
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