PD 134922

Names

[ CAS No. ]:
150351-30-7

[ Name ]:
PD 134922

Biological Activity

[Description]:

PD 134922 is a potent renin and HIV-1 protease inhibitor with an IC50 of 15 nM against HIV-1 protease[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease
Signaling Pathways >> Metabolic Enzyme/Protease >> Renin

[Target]

IC50: 15 nM (HIV-1 protease)[1]


[References]

[1]. Humblet CC, et al. Characterization of two structurally novel HIV-1 protease inhibitors identified by rational selection. Antiviral Res. 1993 May;21(1):73-84.  

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Molecular Formula ]:
C37H61N5O7S

[ Molecular Weight ]:
719.97500

[ Exact Mass ]:
719.42900

[ PSA ]:
185.02000

[ LogP ]:
7.15040

[ Index of Refraction ]:
1.565