(S)-WAY 100135

Modify Date: 2024-01-01 18:46:36

(S)-WAY 100135 structure	Common Name	(S)-WAY 100135
	CAS Number	149007-54-5	Molecular Weight	468.46
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₃₅Cl₂N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (S)-WAY 100135

(S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].

Name	(2S)-3-[4-(2-Methoxyphenyl)-1-piperazinyl]-N-(2-methyl-2-propanyl )-2-phenylpropanamide dihydrochloride

Description	(S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Cliffe IA, et al. (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J Med Chem. 1993 May 14;36(10):1509-10.

Molecular Formula	C₂₄H₃₅Cl₂N₃O₂
Molecular Weight	468.46
Exact Mass	467.21100
PSA	48.30000
LogP	5.96290