GnRH Associated Peptide (1-24), human

Modify Date: 2023-01-04 23:56:44

GnRH Associated Peptide (1-24), human Structure
GnRH Associated Peptide (1-24), human structure
Common Name GnRH Associated Peptide (1-24), human
CAS Number 148943-65-1 Molecular Weight 2732.95
Density N/A Boiling Point N/A
Molecular Formula C117H190N32O43 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GnRH Associated Peptide (1-24), human


GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1].

 Names

Name GnRH Associated Peptide (1-24), human

 GnRH Associated Peptide (1-24), human Biological Activity

Description GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1].
Related Catalog
In Vitro GAP (10 nM; 4 h) stimulates the release of both gonadotropins in anterior pituitaries from female Sprague-Dawley rats, but inhibits the basal secretion of prolactin by ~50%, compared with inhibition levels reported for dopamin, a known prolactin-inhibiting factor[2]. GAP (0.1-10 nM; 3-4 h) inhibits prolactin secretion by 40-45%, with an IC50 value of 0.25 nM[2].

 Chemical & Physical Properties

Molecular Formula C117H190N32O43
Molecular Weight 2732.95