148943-65-1
148943-65-1 structure
- Name: GnRH Associated Peptide (1-24), human
- Chemical Name: GnRH Associated Peptide (1-24), human
- CAS Number: 148943-65-1
- Molecular Formula: C117H190N32O43
- Molecular Weight: 2732.95
- Catalog: Signaling Pathways GPCR/G Protein GNRH Receptor
- Create Date: 2022-12-01 14:32:37
- Modify Date: 2023-01-04 23:56:44
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GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1].
| Name | GnRH Associated Peptide (1-24), human |
|---|
| Description | GnRH Associated Peptide (GAP) (1-24), human is the human gonadotropin-releasing hormone-associated peptide (GAP) 1-24 fragment (hGAP-1-24). GAP is joined to the luteinizing hormone-releasing hormone (LH-RH) sequence by a 3 amino acid processing site[1]. |
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| Related Catalog | |
| In Vitro | GAP (10 nM; 4 h) stimulates the release of both gonadotropins in anterior pituitaries from female Sprague-Dawley rats, but inhibits the basal secretion of prolactin by ~50%, compared with inhibition levels reported for dopamin, a known prolactin-inhibiting factor[2]. GAP (0.1-10 nM; 3-4 h) inhibits prolactin secretion by 40-45%, with an IC50 value of 0.25 nM[2]. |
| Molecular Formula | C117H190N32O43 |
|---|---|
| Molecular Weight | 2732.95 |