LY300503

Modify Date: 2024-01-14 18:44:36

LY300503 Structure
LY300503 structure
Common Name LY300503
CAS Number 148905-79-7 Molecular Weight 249.74
Density N/A Boiling Point N/A
Molecular Formula C14H16ClNO Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY300503


LY300503 is an enantiomer of LY191704. LY191704 is a human type I 5α-reductase inhibitor[1][2].

 Names

Name LY300503

 LY300503 Biological Activity

Description LY300503 is an enantiomer of LY191704. LY191704 is a human type I 5α-reductase inhibitor[1][2].
Related Catalog
In Vivo LY300503 (30-300 mg/kg; p.o. for 14 d) exhibits the mean dose-normalized AUC value of 56% after the first dose and 38% after the last dose in rats[2].
References

[1]. Farid NA, et, al. High-performance liquid chromatographic determination of the enantiomers of the benzoquinolinone LY191704, a human type 1 5 alpha-reductase inhibitor, in plasma. J Chromatogr B Biomed Sci Appl.

[2]. Farid NA, et, al. Stereoselective disposition of the enantiomers of the benzoquinolinone LY191704, a human type I 5 alpha-reductase inhibitor. Differences between rats and dogs. Drug Metab Dispos. 1996 Oct;24(10):1162-5.

 Chemical & Physical Properties

Molecular Formula C14H16ClNO
Molecular Weight 249.74
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