Fmoc-Thr(TBDMS)-OH

Modify Date: 2024-01-10 17:20:31

Fmoc-Thr(TBDMS)-OH Structure
Fmoc-Thr(TBDMS)-OH structure
Common Name Fmoc-Thr(TBDMS)-OH
CAS Number 146346-82-9 Molecular Weight 455.61900
Density N/A Boiling Point 577.2±50.0°C
Molecular Formula C25H33NO5Si Melting Point N/A
MSDS USA Flash Point N/A

 Use of Fmoc-Thr(TBDMS)-OH


Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted therapy[1].

 Names

Name Fmoc-Thr(TBDMS)-OH
Synonym More Synonyms

 Fmoc-Thr(TBDMS)-OH Biological Activity

Description Fmoc-Thr(TBDMS)-OH is a Threonine derivative. Fmoc-Thr(TBDMS)-OH can be used for the preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted therapy[1].
Related Catalog
References

[1]. Uehara Keiji, et al. Preparation of sugar ligand-tethered functional nucleic acid conjugates for targeted therapy. Patent CA3012967.

 Chemical & Physical Properties

Boiling Point 577.2±50.0°C
Molecular Formula C25H33NO5Si
Molecular Weight 455.61900
Exact Mass 455.21300
PSA 84.86000
LogP 5.77950

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

~87%

Fmoc-Thr(TBDMS)-OH Structure

Fmoc-Thr(TBDMS)-OH

CAS#:146346-82-9

Literature: Huang, Yi-Chao; Li, Yi-Ming; Chen, Yang; Pan, Man; Li, Yi-Tong; Yu, Li; Guo, Qing-Xiang; Liu, Lei Angewandte Chemie - International Edition, 2013 , vol. 52, # 18 p. 4858 - 4862 Angew. Chem., 2013 , vol. 125, # 18 p. 4958 - 4962

~%

Fmoc-Thr(TBDMS)-OH Structure

Fmoc-Thr(TBDMS)-OH

CAS#:146346-82-9

Literature: Tetrahedron Letters, , vol. 42, # 23 p. 3807 - 3809

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Fmoc-Thr(TBDMS)-OH Structure

Fmoc-Thr(TBDMS)-OH

CAS#:146346-82-9

Literature: Tetrahedron Letters, , vol. 33, # 49 p. 7605 - 7608

~%

Fmoc-Thr(TBDMS)-OH Structure

Fmoc-Thr(TBDMS)-OH

CAS#:146346-82-9

Literature: Tetrahedron Letters, , vol. 42, # 23 p. 3807 - 3809

 Synonyms

(2S,3R)-3-[tert-butyl(dimethyl)silyl]oxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid