Mitiglinide (Calcium)
Mitiglinide (Calcium) structure
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Common Name | Mitiglinide (Calcium) | ||
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| CAS Number | 145525-41-3 | Molecular Weight | 334.44 | |
| Density | 1.175 | Boiling Point | 519.6ºC at 760 mmHg | |
| Molecular Formula | C19H24NO3Ca0.5 | Melting Point | 146-148ºC | |
| MSDS | USA | Flash Point | 268ºC | |
Use of Mitiglinide (Calcium)Mitiglinide(KAD-1229; S21403) is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. IC50 value:Target: KATP channelMitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)-sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells. Mitiglinide stimulates insulin secretion by stimulating Ca2+ influx. |
| Name | Calcium 2-benzyl-4-((3aR,7aS)-hexahydro-1H-isoindol-2(3H)-yl)-4-oxobutanoate |
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| Synonym | More Synonyms |
| Description | Mitiglinide(KAD-1229; S21403) is a drug for the treatment of type 2 diabetes; it is a highly selective KATP channel antagonist. IC50 value:Target: KATP channelMitiglinide is a hypoglycemic agent that closes adenosine triphosphate (ATP)-sensitive potassium channels (KATP channel s) in the pancreatic β-islet cells. Mitiglinide stimulates insulin secretion by stimulating Ca2+ influx. |
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| Related Catalog | |
| References |
| Density | 1.175 |
|---|---|
| Boiling Point | 519.6ºC at 760 mmHg |
| Melting Point | 146-148ºC |
| Molecular Formula | C19H24NO3Ca0.5 |
| Molecular Weight | 334.44 |
| Flash Point | 268ºC |
| PSA | 102.45000 |
| LogP | 5.59450 |
| Vapour Pressure | 1.27E-11mmHg at 25°C |
| Storage condition | room temp |
| HS Code | 2942000000 |
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Efficacy and safety of mitiglinide versus nateglinide in newly diagnose patients with type 2 diabetes mellitus: a randomized double blind trial.
Diabetes Obes. Metab. 14(2) , 187-9, (2012) This study was performed to examine the efficacy and safety of mitiglinide in type 2 diabetes patients (T2DM). Enrolled patients had received treatment with diet and exercise in the previous 3 months ... |
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Comparison of the rapidity of onset of the therapeutic effect between nateglinide and mitiglinide by PK/PD analysis in rats.
Eur. J. Drug Metab. Pharmacokinet. 37(1) , 9-15, (2012) Nateglinide and mitiglinide are immediate short-acting insulinotropic agents. Both are administered preprandially to control postprandial hyperglycemia. Glinide drugs are characterized by immediate on... |
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Variations in tissue selectivity amongst insulin secretagogues: a systematic review.
Diabetes Obes. Metab. 14(2) , 130-8, (2012) Insulin secretagogues promote insulin release by binding to sulfonylurea receptors on pancreatic β-cells (SUR1). However, these drugs also bind to receptor isoforms on cardiac myocytes (SUR2A) and vas... |
| Mitiglinide |
| Mitiglinide calcium |
| MFCD08458378 |
| (aS,3aR,7aS)-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calcium salt |
| [2(S)-cis]-Octahydro-g-oxo-a-(phenylmethyl)-2H-isoindole-2-butanoic acid calclium salt |
| Mitiglinide hemicalcium salt |
| Mitiglinide (Calcium) |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Mitiglinide (Calcium)
- Price: ￥2198.0/250mg ￥778.0/50mg
- Purity: 99.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Mitiglinide Calcium
- Price: $300.0/100mg $600.0/250mg $1200.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Mitiglinide
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Mitiglinide calcium
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
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