T326

Modify Date: 2024-04-08 16:29:01

T326 Structure
T326 structure
Common Name T326
CAS Number 1451042-19-5 Molecular Weight 434.474
Density N/A Boiling Point N/A
Molecular Formula C21H18N6O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of T326


A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits.

 Names

Name T326

 T326 Biological Activity

Description A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits.
References References 1. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669. View Related Products by Target HDAC

 Chemical & Physical Properties

Molecular Formula C21H18N6O3S
Molecular Weight 434.474
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