T326

Names

[ Name ]:
T326

Biological Activity

[Description]:

A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits.

[References]

References 1. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669. View Related Products by Target HDAC

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₈N₆O₃S

[ Molecular Weight ]:
434.474

Related Compounds

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