1451042-19-5
1451042-19-5 structure
- Name: T326
- Chemical Name: T326
- CAS Number: 1451042-19-5
- Molecular Formula: C21H18N6O3S
- Molecular Weight: 434.474
- Catalog: Signaling Pathways Anti-infection HIV
- Create Date: 2020-01-12 11:34:50
- Modify Date: 2024-04-08 16:29:01
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A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits.
| Name | T326 |
|---|
| Description | A potent and selective HDAC3 inhibitor with IC50 of 0.26 uM, with no activity against HDAC1/4/6/8; induces dose-dependent selective increase of NF-κB acetylation in human colon cancer HCT116 cells, induces growth inhibition of cancer cells, and activates HIV gene expression in latent HIV-infected cells; shows promising activity for anticancer and antiviral benefits. |
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| References | References 1. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669. View Related Products by Target HDAC |
| Molecular Formula | C21H18N6O3S |
|---|---|
| Molecular Weight | 434.474 |