Amgen-23

Modify Date: 2024-01-02 11:06:08

Amgen-23 structure	Common Name	Amgen-23
	CAS Number	1448706-15-7	Molecular Weight	478.43
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₅Cl₂N₃O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Amgen-23

Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer[1].

Name	Amgen-23

Description	Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> SPHK
Target	SphK1:20 nM (IC50) SphK2:1.6 μM (IC50)
References	[1]. Gustin DJ, et al. Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4608-16.

Molecular Formula	C₂₃H₂₅Cl₂N₃O₂S
Molecular Weight	478.43
Storage condition	-20°C