GCN2-IN-1

Modify Date: 2024-02-02 21:54:35

GCN2-IN-1 Structure
GCN2-IN-1 structure
Common Name GCN2-IN-1
CAS Number 1448693-69-3 Molecular Weight 402.413
Density 1.7±0.1 g/cm3 Boiling Point 760.0±70.0 °C at 760 mmHg
Molecular Formula C19H18N10O Melting Point N/A
MSDS N/A Flash Point 413.4±35.7 °C

 Use of GCN2-IN-1


GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with IC50s of <0.3 μM in the enzyme and cell assay.

 Names

Name GCN2-IN-1
Synonym More Synonyms

 GCN2-IN-1 Biological Activity

Description GCN2-IN-1 is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with IC50s of <0.3 μM in the enzyme and cell assay.
Related Catalog
Target

IC50: <0.3 μM (GCN2)[1]

In Vitro GCN2-IN-1 (Compound A-92) is a GCN2 inhibitor, which may be useful as a chemotherapeutic drug for the treatment of cancer[1].
References

[1]. Brazeau JF, et al. Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2. ACS Med Chem Lett. 2014 Feb 12;5(4):282-3.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 760.0±70.0 °C at 760 mmHg
Molecular Formula C19H18N10O
Molecular Weight 402.413
Flash Point 413.4±35.7 °C
Exact Mass 402.166504
LogP 0.87
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.902
Storage condition -20℃

 Synonyms

MFCD30345302
3-(1H-Indazol-6-yl)-N-[1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine
3H-1,2,3-Triazolo[4,5-d]pyrimidin-5-amine, 3-(1H-indazol-6-yl)-N-[1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: GCN2-IN-1
  • Price: $700.0/100mg $1200.0/250mg $2500.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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Price: $198/10mM*1mLinDMSO

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