VH-032
Modify Date: 2025-08-25 16:10:42
VH-032 structure
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Common Name | VH-032 | ||
|---|---|---|---|---|
| CAS Number | 1448188-62-2 | Molecular Weight | 472.604 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H32N4O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VH-032VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM. |
| Name | VH-032 |
|---|
| Description | VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM. |
|---|---|
| References | References 1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. 2. Galdeano C, et al. J Med Chem. 2014 Oct 23;57(20):8657-63. View Related Products by Target E3 Ligase Ligand |
| Molecular Formula | C24H32N4O4S |
|---|---|
| Molecular Weight | 472.604 |
| InChIKey | GFVIEZBZIUKYOG-SVFBPWRDSA-N |
| SMILES | CC(=O)NC(C(=O)N1CC(O)CC1C(=O)NCc1ccc(-c2scnc2C)cc1)C(C)(C)C |
| Storage condition | -20°C |