VH-032

Modify Date: 2024-01-03 09:21:29

VH-032 Structure
VH-032 structure
Common Name VH-032
CAS Number 1448188-62-2 Molecular Weight 472.604
Density N/A Boiling Point N/A
Molecular Formula C24H32N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of VH-032


VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM.

 Names

Name VH-032

 VH-032 Biological Activity

Description VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM.
References References 1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. 2. Galdeano C, et al. J Med Chem. 2014 Oct 23;57(20):8657-63. View Related Products by Target E3 Ligase Ligand

 Chemical & Physical Properties

Molecular Formula C24H32N4O4S
Molecular Weight 472.604
Storage condition -20°C