VH-032
Names
[ CAS No. ]:
1448188-62-2
[ Name ]:
VH-032
Biological Activity
[Description]:
VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM.
[References]
References 1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7. 2. Galdeano C, et al. J Med Chem. 2014 Oct 23;57(20):8657-63. View Related Products by Target E3 Ligase Ligand
Chemical & Physical Properties
[ Molecular Formula ]:
C24H32N4O4S
[ Molecular Weight ]:
472.604
[ Storage condition ]:
-20°C