Lubeluzole
Modify Date: 2025-08-27 17:13:51
Lubeluzole structure
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Common Name | Lubeluzole | ||
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| CAS Number | 144665-07-6 | Molecular Weight | 433.51500 | |
| Density | 1.327g/cm3 | Boiling Point | 579.8ºC at 760mmHg | |
| Molecular Formula | C22H25F2N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 304.5ºC | |
Use of LubeluzoleLubeluzole is a neuroprotective anti-ischemic compound. Lubeluzole, but not its (-)-R-isomer, protects against sensorimotor deficits provoked by photochemical stroke in rats. Lubeluzole inhibited glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with an IC50 of 37 nM. Lubeluzole also has the potential for developing a novel class of antibacterial adjuvants endowed with spasmolytic activity[1][2]. |
| Name | (2S)-1-[4-[1,3-benzothiazol-2-yl(methyl)amino]piperidin-1-yl]-3-(3,4-difluorophenoxy)propan-2-ol |
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| Synonym | More Synonyms |
| Description | Lubeluzole is a neuroprotective anti-ischemic compound. Lubeluzole, but not its (-)-R-isomer, protects against sensorimotor deficits provoked by photochemical stroke in rats. Lubeluzole inhibited glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with an IC50 of 37 nM. Lubeluzole also has the potential for developing a novel class of antibacterial adjuvants endowed with spasmolytic activity[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.327g/cm3 |
|---|---|
| Boiling Point | 579.8ºC at 760mmHg |
| Molecular Formula | C22H25F2N3O2S |
| Molecular Weight | 433.51500 |
| Flash Point | 304.5ºC |
| Exact Mass | 433.16400 |
| PSA | 77.07000 |
| LogP | 3.85290 |
| Vapour Pressure | 2.75E-14mmHg at 25°C |
| Index of Refraction | 1.632 |
| Prosynap |
| Lubeluzole |