PEG5-bis-(ethyl phosphonate)

Modify Date: 2025-09-24 18:03:42

PEG5-bis-(ethyl phosphonate) Structure
PEG5-bis-(ethyl phosphonate) structure
 Common Name PEG5-bis-(ethyl phosphonate)
CAS Number 1446282-28-5 Molecular Weight 522.5
Density N/A Boiling Point N/A
Molecular Formula C20H44O11P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PEG5-bis-(ethyl phosphonate)


PEG5-bis-(Ethyl phosphonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name PEG5-bis-(ethyl phosphonate)
Synonym More Synonyms

 PEG5-bis-(ethyl phosphonate) Biological Activity

Description PEG5-bis-(Ethyl phosphonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H44O11P2
Molecular Weight 522.5

 Synonyms

MFCD25424124
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