Name | Tetraethyl [oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis(phosphonate) |
---|---|
Synonyms |
Tetraethyl [oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis(phosphonate)
MFCD00778113 Phosphonic acid, P,P'-[oxybis(2,1-ethanediyloxy-2,1-ethanediyl)]bis-, tetraethyl ester |
Description | PEG3-bis-(ethyl phosphonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
---|---|
Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.1±0.1 g/cm3 |
---|---|
Boiling Point | 510.5±45.0 °C at 760 mmHg |
Molecular Formula | C16H36O9P2 |
Molecular Weight | 434.399 |
Flash Point | 275.6±49.1 °C |
Exact Mass | 434.183441 |
LogP | -1.19 |
Vapour Pressure | 0.0±1.3 mmHg at 25°C |
Index of Refraction | 1.443 |