Endothelin-1 (11-21) trifluoroacetate salt

Modify Date: 2024-01-11 08:47:35

Endothelin-1 (11-21) trifluoroacetate salt Structure
Endothelin-1 (11-21) trifluoroacetate salt structure
Common Name Endothelin-1 (11-21) trifluoroacetate salt
CAS Number 144602-02-8 Molecular Weight 1409.67000
Density 1.282g/cm3 Boiling Point 1720.5ºC at 760 mmHg
Molecular Formula C68H92N14O15S2 Melting Point N/A
MSDS N/A Flash Point 994.3ºC

 Use of Endothelin-1 (11-21) trifluoroacetate salt


IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1].

 Names

Name [Cys11-Cys15]-endothelin-1(11-21)
Synonym More Synonyms

  Biological Activity

Description IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1].
Related Catalog
Target

Ki: 6-11 nM (endothelin B receptors), 0.4-0.7 μM (endothelin A receptors)[1]

References

[1]. Urade Y, et al. An endothelin B receptor-selective antagonist: IRL 1038, [Cys11-Cys15]-endothelin-1(11-21). FEBS Lett. 1992 Oct 12;311(1):12-6. doi: 10.1016/0014-5793(92)81355-p.  

 Chemical & Physical Properties

Density 1.282g/cm3
Boiling Point 1720.5ºC at 760 mmHg
Molecular Formula C68H92N14O15S2
Molecular Weight 1409.67000
Flash Point 994.3ºC
Exact Mass 1408.63000
PSA 506.92000
LogP 6.15200
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.59

 Synonyms

cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp