Landiolol Hydrochloride

Modify Date: 2024-01-02 18:03:04

Landiolol Hydrochloride Structure
Landiolol Hydrochloride structure
 Common Name Landiolol Hydrochloride
CAS Number 144481-98-1 Molecular Weight 546.053
Density 1.201g/cm3 Boiling Point 727.5ºC at 760mmHg
Molecular Formula C25H40ClN3O8 Melting Point 122-127ºC
MSDS N/A Flash Point 393.8ºC

 Use of Landiolol Hydrochloride


Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist[1].

 Names

Name Landiolol hydrochloride
Synonym More Synonyms

 Landiolol Hydrochloride Biological Activity

Description Landiolol hydrochloride (ONO1101 hydrochloride) is a highly beta1 selective ultra-short acting beta-blocker (β1/β2 selectivity = 255:1, a half-life of 4 min)， acts as an adrenoceptor antagonist[1].
Related Catalog
Target

beta-adrenergic receptor[1]

References

[1]. Atarashi H, et al. Pharmacokinetics of landiolol hydrochloride, a new ultra-short-acting beta-blocker, in patients with cardiac arrhythmias. Clin Pharmacol Ther. 2000 Aug;68(2):143-50.

[2]. Okajima M, et al. Landiolol, an ultra-short-acting β1-blocker, is useful for managing supraventricular tachyarrhythmias in sepsis. World J Crit Care Med. 2015 Aug 4;4(3):251-7.

 Chemical & Physical Properties

Density 1.201g/cm3
Boiling Point 727.5ºC at 760mmHg
Melting Point 122-127ºC
Molecular Formula C25H40ClN3O8
Molecular Weight 546.053
Flash Point 393.8ºC
Exact Mass 545.250366
PSA 127.82000
LogP 2.37760
Vapour Pressure 3.24E-22mmHg at 25°C

 Safety Information

RTECS DA8346700

 Synthetic Route

N-(2-Aminoethyl)-4-morpholinecarboxamide oxalate structure

N-(2-Aminoethyl...

CAS#:154467-16-0

4-Hydroxybenzenepropanoic acid [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester structure

4-Hydroxybenzen...

CAS#:144256-11-1

Epichlorohydrin structure

Epichlorohydrin

CAS#:106-89-8

~48%

Landiolol Hydrochloride Structure

Landiolol Hydro...

CAS#:144481-98-1

Literature: Procos S.p.A.; Garavaglia, Fabio; Roletto, Jacopo; Paissoni, Paolo Patent: EP2687521 A1, 2014 ; Location in patent: Paragraph 0053; 0054; 0055; 0056; 0057 ;
Landiolol structure

Landiolol

CAS#:133242-30-5

~77%

Landiolol Hydrochloride Structure

Landiolol Hydro...

CAS#:144481-98-1

Literature: Procos S.p.A.; Garavaglia, Fabio; Roletto, Jacopo; Paissoni, Paolo Patent: EP2687521 A1, 2014 ; Location in patent: Paragraph 0051; 0052 ;
4-Hydroxybenzenepropanoic acid [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester structure

4-Hydroxybenzen...

CAS#:144256-11-1

~%

Landiolol Hydrochloride Structure

Landiolol Hydro...

CAS#:144481-98-1

Literature: EP2687521 A1, ;

 Synonyms

((S)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-((S)-2-hydroxy-3-(2-(morpholine-4-carboxamido)ethylamino)propoxy)phenyl)propanoate hydrochloride
[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(2S)-2-hydroxy-3-[2-(morpholine-4-carbonylamino)ethylamino]propoxy]phenyl]propanoate hydrochloride
(-)-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-3-[4-[(S)-2-hydroxy-3-(2-morpholinocarbonylamino)ethylamino]propoxy]phenylpropionic acid hydrochloride
(-)-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-[4-[(S)-2-hydroxy-3-(2-(morpholinocarbonylamino)ethylamino)propoxy]phenyl]propionate monohydrochloride
Benzenepropanoic acid,4-(2-hydroxy-3-((2-((4-morpholinylcarbonyl)amino)ethyl)amino)propoxy)-,(2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester,(S-(R*,R*))-,hydrochloride
Landiololhydrochloride
Benzenepropanoic acid, 4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester, hydrochloride (1:1)
Ono 1101 hydrochloride
2,2-dimethyl-1,3-dioxolan-4S-yl-methyl 3-[P-{3-{(2-(morpholinocarbonylamino)ethyl)amino}-2S-hydroxypropoxy}phenyl] propionate hydrochloride
[(4S)-2,2-Dimethyl-1,3-dioxolan-4-yl]methyl 3-{4-[(2S)-2-hydroxy-3-({2-[(4-morpholinylcarbonyl)amino]ethyl}amino)propoxy]phenyl}propanoate hydrochloride (1:1)
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Landiolol Hydrochloride suppliers

Price: ￥500/5 mg

Reference only. check more Landiolol Hydrochloride price

Related Compounds: More...
Landiolol Hydrochloride Enantiomer Ⅱ
1253907-85-5
Landiolol Hydrochloride Enantiomer Ⅲ
1253907-81-1
Landiolol Impurity 7
144256-26-8
Landiolol Impurity 8
144256-25-7
Triprolidine hydrochloride
6138-79-0
neomycin hydrochloride
1406-02-6
dodecylamine hydrochloride
929-73-7
Tyrocidine, hydrochloride
1406-14-0
Minoxidil hydrochloride
127228-87-9
Norpinan-1-ylhydrazine
2920406-58-0
3-Butylbicyclo[1.1.1]pentan-1-ol
2768366-33-0
Oric-533 tfa
2641307-46-0
Bis[2-(dimethylamino-kappaN)ethanolato-kappaO]bis[mu-[ethyl 3-(oxo-kappaO)butanoato-kappaOa(2)]]bis[1-(methoxy-kappaO)-2-propanolato-kappaO]di-aluminum
149057-70-5
1-(1-Chlorobutyl)-4-(trifluoromethyl)benzene
1696109-20-2
1,3,4-Oxadiazole-2-carboxylic acid;sodium hydride
2940943-92-8
3H-Indolium, 3-ethyl-1,3-dimethyl-2-[(2-methyl-2-phenylhydrazinylidene)methyl]-, bis[2-(hydroxy-kappaO)-5-nitro-3-[2-[2-(oxo-kappaO)-1-[(phenylamino)carbonyl]propyl]diazenyl-kappaN1]benzenesulfonato(3-)]chromate(3-) (3:1)
73398-67-1
Octasodium;5-chloro-3-[[3-methyl-5-oxido-1-(4-sulfonatosulfanylphenyl)pyrazol-4-yl]diazenyl]-2-oxidobenzenesulfonate;chromium(3+);3-methyl-4-[[3-[2-[[4-[[3-methyl-5-oxido-1-(4-sulfonatosulfanylphenyl)pyrazol-4-yl]diazenyl]-3-oxidophenyl]sulfonylamino]ethylsulfamoyl]-2-oxidophenyl]diazenyl]-5-oxido-1-(4-sulfonatosulfanylphenyl)pyrazole
73398-68-2
Cuprate(3-), [2-[2-[4-[2-[6-[(4-amino-6-fluoro-1,3,5-triazin-2-yl)methylamino]-1-(hydroxy-kappaO)-3-sulfo-2-naphthalenyl]diazenyl-kappaN1]-5-(hydroxy-kappaO)-2-methylphenyl]diazenyl]-1,4-benzenedisulfonato(5-)]-, sodium (1:3)
70529-02-1
1,3-thiazol-2-((2)H)amine
7210-72-2
Chemsrc provides Landiolol Hydrochloride(CAS#:144481-98-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Landiolol Hydrochloride are included as well.>> amp version: Landiolol Hydrochloride

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved