ICMT-IN-53

Modify Date: 2024-01-09 18:27:01

ICMT-IN-53 Structure
ICMT-IN-53 structure
Common Name ICMT-IN-53
CAS Number 1443253-17-5 Molecular Weight 409.58
Density N/A Boiling Point N/A
Molecular Formula C26H36FN3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ICMT-IN-53


ICMT-IN-53 (compound 12) is an ICMT inhibitor (IC50=0.96 μM) with PAMPA permeability and antiproliferative activity. ICMT-IN-53 inhibits the proliferation of MDA-MB-231 and PC3 with IC50s of 5.14 μM and 5.88 μM, respectively[1].

 Names

Name ICMT-IN-53

 ICMT-IN-53 Biological Activity

Description ICMT-IN-53 (compound 12) is an ICMT inhibitor (IC50=0.96 μM) with PAMPA permeability and antiproliferative activity. ICMT-IN-53 inhibits the proliferation of MDA-MB-231 and PC3 with IC50s of 5.14 μM and 5.88 μM, respectively[1].
Related Catalog
Target

IC50: 0.96 μM (ICMT)[1]

References

[1]. Ramanujulu PM, et al. Functionalized indoleamines as potent, drug-like inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt). Eur J Med Chem. 2013 May;63:378-86.  

 Chemical & Physical Properties

Molecular Formula C26H36FN3
Molecular Weight 409.58
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