1443253-17-5

1443253-17-5 structure
1443253-17-5 structure
  • Name: ICMT-IN-53
  • Chemical Name: ICMT-IN-53
  • CAS Number: 1443253-17-5
  • Molecular Formula: C26H36FN3
  • Molecular Weight: 409.58
  • Catalog: Research Areas Cancer
  • Create Date: 2024-01-09 18:27:01
  • Modify Date: 2024-01-09 18:27:01
  • ICMT-IN-53 (compound 12) is an ICMT inhibitor (IC50=0.96 μM) with PAMPA permeability and antiproliferative activity. ICMT-IN-53 inhibits the proliferation of MDA-MB-231 and PC3 with IC50s of 5.14 μM and 5.88 μM, respectively[1].

Name ICMT-IN-53
Description ICMT-IN-53 (compound 12) is an ICMT inhibitor (IC50=0.96 μM) with PAMPA permeability and antiproliferative activity. ICMT-IN-53 inhibits the proliferation of MDA-MB-231 and PC3 with IC50s of 5.14 μM and 5.88 μM, respectively[1].
Related Catalog
Target

IC50: 0.96 μM (ICMT)[1]

References

[1]. Ramanujulu PM, et al. Functionalized indoleamines as potent, drug-like inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt). Eur J Med Chem. 2013 May;63:378-86.  

Molecular Formula C26H36FN3
Molecular Weight 409.58
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