(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane

Modify Date: 2024-01-12 18:21:16

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Structure
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane structure
Common Name (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
CAS Number 144164-11-4 Molecular Weight 425.544
Density 1.3±0.1 g/cm3 Boiling Point 656.1±55.0 °C at 760 mmHg
Molecular Formula C23H27N3O3S Melting Point N/A
MSDS N/A Flash Point 350.6±31.5 °C

 Names

Name Thiazol-5-ylmethyl ((2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl)carbamate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 656.1±55.0 °C at 760 mmHg
Molecular Formula C23H27N3O3S
Molecular Weight 425.544
Flash Point 350.6±31.5 °C
Exact Mass 425.177307
PSA 125.71000
LogP 3.27
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.620

 Safety Information

Hazard Codes Xi

 Synthetic Route

~96%

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Structure

(2S,3S,5S)-5-Am...

CAS#:144164-11-4

Literature: ABBOTT LABORATORIES Patent: WO2008/27932 A2, 2008 ; Location in patent: Page/Page column 96 ; WO 2008/027932 A2

~15%

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Structure

(2S,3S,5S)-5-Am...

CAS#:144164-11-4

Literature: Abbott Laboratories Patent: US5559158 A1, 1996 ;

~69%

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Structure

(2S,3S,5S)-5-Am...

CAS#:144164-11-4

Literature: Abbott Laboratories Patent: US5559158 A1, 1996 ;

~%

(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Structure

(2S,3S,5S)-5-Am...

CAS#:144164-11-4

Literature: Journal of the American Chemical Society, , vol. 121, # 6 p. 1145 - 1155

 Synonyms

1,3-Thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenyl-2-hexanyl]carbamate
1,3-Thiazol-5-ylmethyl [(2S,3S,5S)-5-amino-3-hydroxy-1,6-diphenylhexan-2-yl]carbamate
Carbamic acid, N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-, 5-thiazolylmethyl ester
2S,3S,5S-5-Amino-2-[N-[[(5-thiozolyl)methoxy]carbonyl]amino]-1,6-diphenyl-3-hydroxyhexane
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