![]() Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide structure
|
Common Name | Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amide | ||
---|---|---|---|---|
CAS Number | 143896-17-7 | Molecular Weight | 1980.31 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C95H146N22O24 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Galanin (1-13)-Pro-Pro-(Ala-Leu-)₂Ala amideM40 is a potent, non-selective galanin receptor antagonist. |
Name | m40 |
---|---|
Synonym | More Synonyms |
Description | M40 is a potent, non-selective galanin receptor antagonist. |
---|---|
Related Catalog | |
In Vitro | M40 (1 μM) displaces [mono[125IJodo-Tyr26]galanin from binding sites in the hippocampus, hypothalamus, and spinal cord. M40 has a lower affinity than galanin for all membranes. The IC50 values are 6 nM in the hippocampus, 15 nM in the hypothalamus, 12 nM in the spinal cord, and 3 nM in the insulinoma cells. M40 (1 μM) completely blocks 125I-labeled galanin-binding sites[1]. |
References |
Molecular Formula | C95H146N22O24 |
---|---|
Molecular Weight | 1980.31 |
PSA | 715.21000 |
LogP | 2.82290 |
Storage condition | -20°C |
GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2 |
galanin fragment 1-13-pro-pro-ala-*leu-ala-leu-al |
GALANIN FRAGMENT 1-13-PRO-PRO-ALA-LEU-ALA-LEU-ALA-AMIDE |
8-Bromo-cAMP,sodium salt |
H-GLY-TRP-THR-LEU-ASN-SER-ALA-GLY-TYR-LEU-LEU-GLY-PRO-PRO-PRO-ALA-LEU-ALA-LEU-ALA-NH2 |
GWTLNSAGYLLGPPPALALA-NH2 |