Antibiotic 1142

Modify Date: 2024-01-03 11:50:10

Antibiotic 1142 Structure
Antibiotic 1142 structure
 Common Name Antibiotic 1142
CAS Number 1438-30-8 Molecular Weight 430.46400
Density 1.52g/cm3 Boiling Point 544.74°C (rough estimate)
Molecular Formula C18H26N10O3 Melting Point 171-173℃
MSDS N/A Flash Point N/A

 Use of Antibiotic 1142


Netropsin is a basic polypeptide isolated from Streptomyces netropsis. It is cytotoxic and its strong, specific binding to A-T areas of DNA is useful to genetics research. Netropsin is a polyamide with antibiotic and antiviral activity. It has been shown that Netropsin is active both against Gram-positive bacteria and Gram-negative bacteria.

 Names

Name netropsin
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.52g/cm3
Boiling Point 544.74°C (rough estimate)
Melting Point 171-173℃
Molecular Formula C18H26N10O3
Molecular Weight 430.46400
Exact Mass 430.21900
PSA 208.93000
LogP 1.62120
Appearance of Characters powder | faint yellow
Vapour Pressure 1.75E-23mmHg at 25°C
Index of Refraction 1.6500 (estimate)
Storage condition −20°C
Water Solubility H2O: 1 mg/mL

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DW2973000
CHEMICAL NAME :
N,4'-Bi(pyrrole-2-carboxamide), N'-(2-carbamoylethyl)-4-((2-guanidinoacetimidoyl)amin o)-1,1'- dimethyl-
CAS REGISTRY NUMBER :
1438-30-8
BEILSTEIN REFERENCE NO. :
0376913
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C18-H26-N10-O3
MOLECULAR WEIGHT :
430.54
WISWESSER LINE NOTATION :
T5NJ A1 BVM2VZ EMV- BT5NJ A1 DMYUM&1MYZUM

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
70 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
17 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
500 umol/L
REFERENCE :
MLBRBU Molecular Biology Reports. (Dr. W. Junk Pub., POB 163, 3300 AD Dordrect, Netherlands) V.1- 1973- Volume(issue)/page/year: 2,135,1975

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases S36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS DW2973000

 Synonyms

4-{4-[(N-carbamimidoyl-glycyl)-amino]-1-methyl-pyrrole-2-carbonylamino}-1-methyl-pyrrole-2-carboxylic acid-(2-carbamimidoyl-ethylamide)
t1384
Netropsin dihydrochloride
ia887
4-{4-[(N-Carbamimidoyl-glycyl)-amino]-1-methyl-pyrrol-2-carbonylamino}-1-methyl-pyrrol-2-carbonsaeure-(2-carbamimidoyl-aethylamid)
ch-777-a
Congocidin Sinanomycin
congocidin
ultrapuregrade
2814-a
antibiotic1142
Top Suppliers:I want be here

Get all suppliers and price by the below link:

Antibiotic 1142 suppliers

Antibiotic 1142 price

Related Compounds: More...
Antibiotic 1142
554-32-5
2-[3-(diaminomethylideneamino)-4-(3,4-dihydroxy-4,5-dimethyloxolan-2-yl)oxy-2,5,6-trihydroxycyclohexyl]guanidine
99890-21-8
A201A
37305-78-5
Antibiotic SF-973 A
23846-85-7
Antibiotic TS 155-2
303009-07-6
sodium,(5R,6R)-3-[(E)-2-acetamidoethenyl]sulfanyl-6-ethyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
73573-25-8
Antibiotic-5d
251349-54-9
Antibiotic A 83586C
116364-81-9
N-[(E)-2-[(14E)-9-[4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-3-ethyl-7-hydroxy-2,8,12,16-tetramethyl-5,13-dioxo-4,17-dioxabicyclo[14.1.0]heptadec-14-en-10-yl]ethylideneamino]acetamide
130812-04-3
N-(6-benzyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-2-(phenylsulfonyl)acetamide hydrochloride
1216769-71-9
N-(6-benzyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-2-(phenylthio)acetamide hydrochloride
1216976-01-0
4-(methylsulfonyl)-N-(4-(4-phenoxyphenyl)thiazol-2-yl)benzamide
896341-16-5
2-(4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)-N-phenylacetamide
887214-41-7
2-[4-(1H-1,3-benzodiazol-2-yl)piperidin-1-yl]-N-(2,5-dimethylphenyl)acetamide
887214-55-3
N-(1,3-Benzothiazol-2-YL)-N-[2-(dimethylamino)ethyl]-3-methoxybenzamide hydrochloride
1219183-15-9
N-(benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-phenoxybenzamide hydrochloride
1217026-15-7
N-(benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-phenoxyacetamide hydrochloride
1219150-93-2
2-(Benzenesulfonyl)-N-(1,3-benzothiazol-2-YL)-N-[2-(dimethylamino)ethyl]acetamide hydrochloride
1216416-88-4
N-(benzo[d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)-2-tosylacetamide hydrochloride
1216527-08-0
Chemsrc provides Antibiotic 1142(CAS#:1438-30-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Antibiotic 1142 are included as well.>> amp version: Antibiotic 1142

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved