HCH6-1

Modify Date: 2024-01-14 17:12:50

HCH6-1 Structure
HCH6-1 structure
Common Name HCH6-1
CAS Number 1435265-06-7 Molecular Weight 469.53
Density 1.259±0.06 g/cm3(Predicted) Boiling Point 790.8±60.0℃at 760 mmHg
Molecular Formula C28H27N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HCH6-1


HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist). HCH6-1 can be used to treat neutrophilic inflammatory disease due to its inhibitory effects in neutrophil-like cells[1].

 Names

Name HCH6-1
Synonym More Synonyms

 HCH6-1 Biological Activity

Description HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist). HCH6-1 can be used to treat neutrophilic inflammatory disease due to its inhibitory effects in neutrophil-like cells[1].
Related Catalog
References

[1]. Yang SC, et al. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1. Free Radic Biol Med. 2017 May;106:254-269

 Chemical & Physical Properties

Density 1.259±0.06 g/cm3(Predicted)
Boiling Point 790.8±60.0℃at 760 mmHg
Molecular Formula C28H27N3O4
Molecular Weight 469.53

 Safety Information

Hazard Codes Xi

 Synonyms

MFCD32197174
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