HCH6-1

Names

[ Name ]:
HCH6-1

[Synonym ]:
MFCD32197174

Biological Activity

[Description]:

HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist). HCH6-1 can be used to treat neutrophilic inflammatory disease due to its inhibitory effects in neutrophil-like cells[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Yang SC, et al. Dipeptide HCH6-1 inhibits neutrophil activation and protects against acute lung injury by blocking FPR1. Free Radic Biol Med. 2017 May;106:254-269

Chemical & Physical Properties

[ Density]:
1.259±0.06 g/cm3(Predicted)

[ Boiling Point ]:
790.8±60.0℃at 760 mmHg

[ Molecular Formula ]:
C₂₈H₂₇N₃O₄

[ Molecular Weight ]:
469.53

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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