HXJ 42
Modify Date: 2024-01-18 17:44:02
HXJ 42 structure
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Common Name | HXJ 42 | ||
|---|---|---|---|---|
| CAS Number | 1428640-39-4 | Molecular Weight | 352.219 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H15Cl2N5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HXJ 42A PP1 analog that has greater selectivity and potency for Zap-70(AS) over wild-type Zap-70, as assessed by Erk and Lat phosphorylation, as well as by proliferative responses of mature CD4+ cells; effectively rescues Zap70(AS) OT-I cells from negative selection. |
| Name | HXJ 42 |
|---|
| Description | A PP1 analog that has greater selectivity and potency for Zap-70(AS) over wild-type Zap-70, as assessed by Erk and Lat phosphorylation, as well as by proliferative responses of mature CD4+ cells; effectively rescues Zap70(AS) OT-I cells from negative selection. |
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| References | References 1. Au-Yeung BB, et al. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3679-88. 2. Au-Yeung BB, et al. Nat Immunol. 2014 Jul;15(7):687-94. View Related Products by Target T Cell Receptor (TCR) |
| Molecular Formula | C15H15Cl2N5O |
|---|---|
| Molecular Weight | 352.219 |