ML254

Modify Date: 2024-01-10 19:15:04

ML254 structure	Common Name	ML254
	CAS Number	1428630-86-7	Molecular Weight	310.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₅FN₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ML254

ML254 is a potent mGlu5 potentiator, with EC50 and pEC50 of 9.3 nM and 8.03 nM for rat mGlu5, respectively. ML254 can be used for researching schizophrenia[1].

Name	ML 254

Description	ML254 is a potent mGlu5 potentiator, with EC50 and pEC50 of 9.3 nM and 8.03 nM for rat mGlu5, respectively. ML254 can be used for researching schizophrenia[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	rat mGluR5:9.3 nM (EC50) rat mGluR5:8.03 nM (pEC50)
References	[1]. Turlington M, Noetzel MJ, Chun A, et al. Exploration of allosteric agonism structure-activity relationships within an acetylene series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs): discovery of 5-((3-fluorophenyl)ethynyl)-N-(3-methyloxetan-3-yl)picolinamide (ML254). J Med Chem. 2013;56(20):7976-7996.

Molecular Formula	C₁₈H₁₅FN₂O₂
Molecular Weight	310.32

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ML254
Price: Check
Purity: 99.94%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: ML254
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: ML 254
Price: ￥Inquiry/100mg
Purity: 98.0%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

ML254 suppliers