DBCO-​C6-​acid

Modify Date: 2024-01-10 11:21:58

DBCO-​C6-​acid Structure
DBCO-​C6-​acid structure
Common Name DBCO-​C6-​acid
CAS Number 1425485-72-8 Molecular Weight 333.380
Density 1.3±0.1 g/cm3 Boiling Point 634.4±55.0 °C at 760 mmHg
Molecular Formula C21H19NO3 Melting Point N/A
MSDS N/A Flash Point 337.5±31.5 °C

 Use of DBCO-​C6-​acid


DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1].

 Names

Name 6-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-6-oxohexanoic acid
Synonym More Synonyms

 DBCO-​C6-​acid Biological Activity

Description DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1].
Related Catalog
Target

Non-cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References

[1]. Almaliti J, et al. Exploration of the carmaphycins as payloads in antibody drug conjugate anticancer agents.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 634.4±55.0 °C at 760 mmHg
Molecular Formula C21H19NO3
Molecular Weight 333.380
Flash Point 337.5±31.5 °C
Exact Mass 333.136505
LogP 4.48
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.654

 Safety Information

Hazard Codes Xi

 Synonyms

6-(11,12-Didehydrodibenzo[b,f]azocin-5(6H)-yl)-6-oxohexanoic acid
Dibenz[b,f]azocine-5(6H)-hexanoic acid, 11,12-didehydro-ε-oxo-
DBCO acid 3
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  • DC Chemicals Limited
  • China
  • Product Name: DBCO acid 3
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
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