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1353016-70-2

1353016-70-2 structure
1353016-70-2 structure
  • Name: DBCO-acid
  • Chemical Name: 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoic acid
  • CAS Number: 1353016-70-2
  • Molecular Formula: C19H15NO3
  • Molecular Weight: 305.32700
  • Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
  • Create Date: 2018-02-26 05:18:22
  • Modify Date: 2025-09-10 18:40:58
  • DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1].

Name 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoic acid
Synonyms DBCO acid 1
Description DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1].
Related Catalog
Target

Cleavable

References

[1]. Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61.

Molecular Formula C19H15NO3
Molecular Weight 305.32700
Exact Mass 305.10500
PSA 57.61000
LogP 2.86280
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