Piflufolastat

Modify Date: 2025-08-25 18:06:21

Piflufolastat Structure
Piflufolastat structure
Common Name Piflufolastat
CAS Number 1423758-00-2 Molecular Weight 442.39600
Density N/A Boiling Point N/A
Molecular Formula C18H23FN4O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Piflufolastat


Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA)[1].

 Names

Name (2S)-2-[[(1S)-1-carboxy-5-[(6-fluoropyridine-3-carbonyl)amino]pentyl]carbamoylamino]pentanedioic acid
Synonym More Synonyms

 Piflufolastat Biological Activity

Description Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA)[1].
Related Catalog
References

[1]. Keam SJ, et al. Piflufolastat F 18: Diagnostic First Approval. Mol Diagn Ther. 2021 Sep;25(5):647-656.

[2]. Ying Chen, et al. 2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid, [18F]DCFPyL, a PSMA-based PET imaging agent for prostate cancer. Clin Cancer Res. 2011 Dec 15;17(24):7645-53.

 Chemical & Physical Properties

Molecular Formula C18H23FN4O8
Molecular Weight 442.39600
Exact Mass 442.15000
PSA 202.00000
LogP 1.36130

 Synonyms

2-(3-(1-Carboxy-5-((6-fluoro-pyridine-3-carbonyl)-amino)-pentyl)-ureido)-pentanedioic acid
L-Glutamic acid,N-((((1S)-1-carboxy-5-(((6-fluoro-3-pyridinyl)carbonyl)amino)pentyl)amino)carbonyl)
DCFPYL
UNII-82VH67YON8
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