Piflufolastat

Names

[ Name ]:
Piflufolastat

[Synonym ]:
2-(3-(1-Carboxy-5-((6-fluoro-pyridine-3-carbonyl)-amino)-pentyl)-ureido)-pentanedioic acid
L-Glutamic acid,N-((((1S)-1-carboxy-5-(((6-fluoro-3-pyridinyl)carbonyl)amino)pentyl)amino)carbonyl)
DCFPYL
UNII-82VH67YON8

Biological Activity

[Description]:

Piflufolastat (DCFPYL) can be used to the preparation of piflufolastat F 18 (DCFPyL F-18). piflufolastat F 18. Piflufolastat F-18 is an 18F-labelled diagnostic imaging agent. Piflufolastat F-18 can be used for positron emission tomography (PET) that targets prostate-specific membrane antigen (PSMA)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Keam SJ, et al. Piflufolastat F 18: Diagnostic First Approval. Mol Diagn Ther. 2021 Sep;25(5):647-656.

[2]. Ying Chen, et al. 2-(3-{1-Carboxy-5-[(6-[18F]fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid, [18F]DCFPyL, a PSMA-based PET imaging agent for prostate cancer. Clin Cancer Res. 2011 Dec 15;17(24):7645-53.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₃FN₄O₈

[ Molecular Weight ]:
442.39600

[ Exact Mass ]:
442.15000

[ PSA ]:
202.00000

[ LogP ]:
1.36130

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.