S-Acetyl-PEG3-C2-acid

Modify Date: 2024-01-21 02:20:05

S-Acetyl-PEG3-C2-acid Structure
S-Acetyl-PEG3-C2-acid structure
Common Name S-Acetyl-PEG3-C2-acid
CAS Number 1421933-33-6 Molecular Weight 280.338
Density 1.2±0.1 g/cm3 Boiling Point 421.4±40.0 °C at 760 mmHg
Molecular Formula C11H20O6S Melting Point N/A
MSDS N/A Flash Point 208.7±27.3 °C

 Use of S-Acetyl-PEG3-C2-acid


S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name S-acetyl-PEG3-acid
Synonym More Synonyms

 S-Acetyl-PEG3-C2-acid Biological Activity

Description S-Acetyl-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 421.4±40.0 °C at 760 mmHg
Molecular Formula C11H20O6S
Molecular Weight 280.338
Flash Point 208.7±27.3 °C
Exact Mass 280.098053
LogP -0.17
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.489

 Synonyms

6,9,12-Trioxa-3-thiapentadecan-15-oic acid, 2-oxo-
2-Oxo-6,9,12-trioxa-3-thiapentadecan-15-oic acid
MFCD22574765