S-Acetyl-PEG3-azide

Modify Date: 2024-01-10 13:38:11

S-Acetyl-PEG3-azide Structure
S-Acetyl-PEG3-azide structure
Common Name S-Acetyl-PEG3-azide
CAS Number 1310827-26-9 Molecular Weight 277.341
Density N/A Boiling Point N/A
Molecular Formula C10H19N3O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S-Acetyl-PEG3-azide


S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name S-Acetyl-PEG3-Azido
Synonym More Synonyms

 S-Acetyl-PEG3-azide Biological Activity

Description S-Acetyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H19N3O4S
Molecular Weight 277.341
Exact Mass 277.109619
LogP 0.31

 Synonyms

Ethanethioic acid, S-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl] ester
S-(2-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}ethyl) ethanethioate
MFCD22201539
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