GN 44028
Modify Date: 2024-01-09 12:35:26
GN 44028 structure
|
Common Name | GN 44028 | ||
|---|---|---|---|---|
| CAS Number | 1421448-26-1 | Molecular Weight | 305.33 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H15N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GN 44028GN44028 is a hypoxia inducible factor (HIF)-1 inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization[1]. |
| Name | GN44028 |
|---|
| Description | GN44028 is a hypoxia inducible factor (HIF)-1 inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity without suppressing HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 14 nM (HIF-1)[1]. |
| References |
| Molecular Formula | C18H15N3O2 |
|---|---|
| Molecular Weight | 305.33 |
| Hazard Codes | Xi |
|---|