PROSTAGLANDIN A1

Modify Date: 2025-08-22 11:15:22

PROSTAGLANDIN A1 Structure
PROSTAGLANDIN A1 structure
 Common Name PROSTAGLANDIN A1
CAS Number 14152-28-4 Molecular Weight 336.466
Density 1.1±0.1 g/cm3 Boiling Point 510.7±50.0 °C at 760 mmHg
Molecular Formula C20H32O4 Melting Point 41 - 43ºC
MSDS Chinese USA Flash Point 276.7±26.6 °C

 Names

Name prostaglandin A1
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 510.7±50.0 °C at 760 mmHg
Melting Point 41 - 43ºC
Molecular Formula C20H32O4
Molecular Weight 336.466
Flash Point 276.7±26.6 °C
Exact Mass 336.230072
PSA 74.60000
LogP 3.61
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.541
Storage condition −20°C
Water Solubility acetone: 10 mg/mL, clear

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GY5977900
CHEMICAL NAME :
3-Cyclopentene-1-heptanoic acid, 2-(3-hydroxy-1-octenyl)-5-oxo-
CAS REGISTRY NUMBER :
14152-28-4
LAST UPDATED :
198910
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H32-O4
MOLECULAR WEIGHT :
336.52
WISWESSER LINE NOTATION :
T5V BUTJ D2YQ5 E6VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
12 mg/kg
SEX/DURATION :
male 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - other effects on male
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
169 ug/kg
SEX/DURATION :
female 17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
169 ug/kg
SEX/DURATION :
female 17 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - urogenital system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
10 mg/kg
SEX/DURATION :
female 16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
40 mg/kg
SEX/DURATION :
female 16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - abortion

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
2500 ug/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,513,1983

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS GY5977900

 Articles38

More Articles
The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes.

J. Immunol. 194(6) , 2776-85, (2015)

Inflammasomes are cytosolic protein complexes that respond to diverse danger signals by activating caspase-1. The sensor components of the inflammasome, often proteins of the nucleotide-binding oligom...

Protective effects of n-6 fatty acids-enriched diet on intestinal ischaemia/reperfusion injury involve lipoxin A4 and its receptor.

Br. J. Pharmacol. 172(3) , 910-23, (2015)

Long-term intake of dietary fatty acids is known to predispose to chronic inflammation, but their effects on acute intestinal ischaemia/reperfusion (I/R) injury is unknown. The aim of this study was t...

Vimentin filament organization and stress sensing depend on its single cysteine residue and zinc binding.

Nat. Commun. 6 , 7287, (2015)

The vimentin filament network plays a key role in cell architecture and signalling, as well as in epithelial-mesenchymal transition. Vimentin C328 is targeted by various oxidative modifications, but i...

 Synonyms

(13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid
(13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid PGA1
(13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid,PGA1
Prosta-10,13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-
Prostaglandin A1
MFCD00077858
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