(R)-PS210

Modify Date: 2024-01-15 18:15:11

(R)-PS210 structure	Common Name	(R)-PS210
	CAS Number	1410101-89-1	Molecular Weight	380.31
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₅F₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R)-PS210

(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment[1].

Name	(R)-PS210

Description	(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-selective allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment[1].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> PDK-1 Research Areas >> Cancer
Target	AC50: 1.8 μM (PDK1)[1]
In Vitro	(R)-PS210 displays an AC50 value of 1.8 μM towards PDK1 in a Cell-Free Kinase Activity Assay. And the maximum activation of PDK1 compared to DMSO control of (R)-PS210 is 5.5 fold[1].
References	[1]. Wilhelm A, et al. 2-(3-Oxo-1,3-diphenylpropyl)malonic acids as potent allosteric ligands of the PIF pocket of phosphoinositide-dependent kinase-1: development and prodrug concept.J Med Chem. 2012 Nov 26;55(22):9817-30.

Molecular Formula	C₁₉H₁₅F₃O₅
Molecular Weight	380.31

DC Chemicals Limited
China
Product Name: (R)-PS210
Price:
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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