flaccidoside II

Modify Date: 2025-08-27 12:19:53

flaccidoside II structure	Common Name	flaccidoside II
	CAS Number	140694-19-5	Molecular Weight	1205.38
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₉H₉₆O₂₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of flaccidoside II

Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome[1][2].

Name	flaccidoside II
Synonym	More Synonyms

Description	Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Inflammation/Immunology
References	[1]. Zhang GB, et al. Corrigendum to "Flaccidoside II ameliorates collagen-induced arthritis in mice" [Eur. J. Pharmacol. 880 (2020) 173155]. Eur J Pharmacol. 2021 Apr 15;897:173963. [2]. Han LT, et al. Triterpenoid saponin flaccidoside II from Anemone flaccida triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors via the MAPK-HO-1 pathway. Onco Targets Ther. 2016 Apr 5;9:1969-79.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Inflammation/Immunology

References

[1]. Zhang GB, et al. Corrigendum to "Flaccidoside II ameliorates collagen-induced arthritis in mice" [Eur. J. Pharmacol. 880 (2020) 173155]. Eur J Pharmacol. 2021 Apr 15;897:173963.

[2]. Han LT, et al. Triterpenoid saponin flaccidoside II from Anemone flaccida triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors via the MAPK-HO-1 pathway. Onco Targets Ther. 2016 Apr 5;9:1969-79.

Molecular Formula	C₅₉H₉₆O₂₅
Molecular Weight	1205.38
Exact Mass	1204.62000
PSA	392.59000
InChIKey	UBTBHOFMNJVLGL-POCFSPCXSA-N
SMILES	CC1OC(OC2C(OC3CCC4(C)C(CCC5(C)C4CC=C4C6CC(C)(C)CCC6(C(=O)OC6OC(COC7OC(OO)C(OC8OC(C)C(O)C(O)C8O)C(O)C7O)C(O)C(O)C6O)CCC45C)C3(C)C)OCC(O)C2O)C(O)C(O)C1O

3-O-[α-L-rhamnopyranosyl-(1->2)-β-D-xylopyranosyl]oleanolic acid 28-O-[α-L-rhamnopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl] ester

3-O-(α-L-rhamnopyranosyl)-(1->2)-(β-D-xylopyranosyl)-oleanolic acid α-L-rhamnopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-α-D-glucopyranosyl ester

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Shanghai Nianxing Industrial Co., Ltd
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Product Name: flaccidoside II
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.