KT182
Modify Date: 2024-01-05 10:54:58
KT182 structure
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Common Name | KT182 | ||
|---|---|---|---|---|
| CAS Number | 1402612-62-7 | Molecular Weight | 438.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H26N4O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of KT182KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells[1]. |
| Name | KT182 |
|---|
| Description | KT182 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.24 nM in Neuro2A cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.24 nM (ABHD6 in Neuro2A cells)[1]. |
| References |
| Molecular Formula | C27H26N4O2 |
|---|---|
| Molecular Weight | 438.52 |
| Storage condition | 2-8℃ |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H413 |
| Precautionary Statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |
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Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6).
J. Med. Chem. 56(21) , 8270-9, (2013) α/β-Hydrolase domain containing 6 (ABHD6) is a transmembrane serine hydrolase that hydrolyzes the endogenous cannabinoid 2-arachidonoylglycerol (2-AG) to regulate certain forms of cannabinoid receptor... |