Zandelisib

Modify Date: 2024-01-03 22:17:05

Zandelisib Structure
Zandelisib structure
Common Name Zandelisib
CAS Number 1401436-95-0 Molecular Weight 576.68
Density N/A Boiling Point 729.2±70.0 °C(Predicted)
Molecular Formula C31H38F2N8O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Zandelisib


Zandelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC50 of 3.5 nM. Zandelisib functions as an antineoplastic[1][2].

 Names

Name Zandelisib

 Zandelisib Biological Activity

Description Zandelisib is a phosphatidylinositol 3-kinase (PI3K) inhibitor extracted from patent WO2019183226 A1, Compound Example 1. Zandelisib selectively inhibits p110δ with an IC50 of 3.5 nM. Zandelisib functions as an antineoplastic[1][2].
Related Catalog
Target

PI3Kδ:3.5 nM (IC50)

In Vitro Zandelisib inhibits PI3Ks with IC50s of 4, 976 nM, 605 nM, 817 nM and 3.5 nM for p110α, p110β, p110γ and p110δ, respectivey[1].
References

[1]. Daniel P. Gold, et al. Combination therapy. WO2019183226A1.

[2]. David Brown, et al. (sulfinyl and sulfonyl benzimidazolyl) pyrimidines and triazines, pharmaceutical compositions thereof, and their use for treating proliferative diseases. WO2014055647A1.

 Chemical & Physical Properties

Boiling Point 729.2±70.0 °C(Predicted)
Molecular Formula C31H38F2N8O
Molecular Weight 576.68
Storage condition -20°C

 Safety Information

Hazard Codes Xn
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Zandelisib
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

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